Extrait

Background and study aims Catheter ablation is a procedure that is used to carefully destroy a diseased area of the heart and interrupt abnormal electrical circuits. This study is designed to compare three different types of catheter commonly used to perform ablations for atrial flutter (abnormal heart rhythm). In particular we are interested to know whether cooling the tip of the catheter by sprinkling water through it (irrigation) at two sites rather than one makes it more effective. Who can participate? Male or female patients aged 18 years or above who are having an ablation procedure to prevent or treat atrial flutter. What does the study involve? Patients will be randomly allocated to be treated with one of the three catheters. We will record how long the procedure takes, how much energy we need to give and how long we X-ray you for. What are the possible benefits and risks of participating? There are no direct benefits to you of taking part in this study. Hopefully our findings will help select the best catheter design for future patients. There are no additional risks to you of taking part in this study above and beyond the risks of the procedure. Catheter ablation is associated with a risk of damage to blood vessels, damage to structures within the heart and leaving people needing a pacemaker afterwards. Sometimes the treatment does not work and people go on experiencing arrhythmias. The ablation procedure is carried out under the guidance of X-rays which deliver a small radiation dose. Partly for this reason this is not a procedure which should normally be carried out if you are pregnant. Where is the study run from? John Radcliffe Hospital (Oxford, UK). When is the study starting and how long is it expected to run for? The study is expected to run from June 2009 to January 2011. Who is funding the study? The study is sponsored by the Oxford Radcliffe Hospitals NHS trust. Who is the main contact? Dr Kim Rajappan [email protected]

Critère d'inclusion

• Atrial flutter

Liens

• isrctn
• ictrp