Extrait

Background and study aims Depression is considered the second leading cause of disability caused by illness affecting about 121 million people around the world. Cognitive behaviour therapy (CBT) is an evidence-based treatment for depression. However, only approximately 5 out of 10 of patients respond and only a third remain recovered at follow-up. Initial studies show that meta-cognitive therapy (MCT) might optimize effectiveness. The present study intents to compare 128 depressed Danish outpatients randomly assigned to up to 24 weekly sessions of either CBT or MCT. The approach of the data-analysis consists of a mixed-model analysis of variance and analysis of co-variance to assess relative treatment effects. The results of the trial will have significant impact on enhancing treatment methods for depression. Who can participate? Participants are patients referred from their general practitioner (GP) to get psychological treatment at the CEKTOS center for their depression who want treatment within 2 weeks and are willing to participate in a trial. What does the study involve? After screening and diagnosis the participants are randomly allocated to receive either treatment as usual - CBT or MCT. Patients who are suitable for the trial receive either up to 24 sessions of CBT or MCT. What are the possible benefits and risks of participating? No known risks or side effects from either CBT or MCT. Where is the study run from? It takes place at CEKTOS Center for Kognitiv Terapi og Supervision in Næstved. Supervision is given at Manchester University where the manager of the trial is a PhD student. When is the study starting and how long is it expected to run for? The trial started in 2010 and is expected to run for at least 4 years. Who is funding the study? It is a privately funded study sponsored by CEKTOS- Center for Kognitiv Terapi og Supervision. Who is the main contact? Pia Callesen [email protected] [email protected]

Critère d'inclusion

• depression

Liens

• ictrp
• isrctn