Extrait

The clinical trial we are proposing directly addresses the problem that at the moment there is no treatment that can stop people with multiple sclerosis (MS) from becoming permanently disabled in the long term by their illness: this usually occurs when people develop the secondary progressive form of MS, where it is believed that the disability arises because of permanent damage to the nerve fibres (axons) in the brain and spinal cord. We propose to test the possibility that the drug lamotrigine has the ability to protect axons from damage in people with secondary progressive MS, and that it can thereby prevent the accumulation of disability.

Critère d'inclusion

• Multiple sclerosis

Liens

• euctr
• ictrp