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Effects of the Soluble Mediators of Mastocytes on the Intestinal Epithelial Barrier and of the Enteric Nervous System During the Syndrome of the Irritable Bowel

Mise à jour : Il y a 4 ans
Référence : NCT00742118

Femme et Homme

  • | Pays :
  • France
  • | Organes :
    • -
  • | Spécialités :
    • -

Extrait

Patients with irritable bowel syndrome (IBS) have increased intestinal permeability. In addition, mucosal soluble mediators are involved in the pathophysiology of pain in IBS. The investigators aimed to investigate: 1. paracellular permeability in colonic biopsies of IBS patient 2. the ability of soluble factors from colonic biopsies to reproduce in vitro these alterations

Critère d'inclusion

  • Irritable bowel syndrome

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