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A diagnostic interventional, controlled, cross-sectional evaluation of joint status using MRI in subjects with severe hemophilia A treated with primary prophylaxis, secondary prophylaxis, or on-demand...

Update Il y a 4 ans
Reference: EUCTR2009-010147-14

A diagnostic interventional, controlled, cross-sectional evaluation of joint status using MRI in subjects with severe hemophilia A treated with primary prophylaxis, secondary prophylaxis, or on-demand therapy

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Extract

To evaluate bone and cartilage damage at different ages using MRI in four index joints of subjects with severe hemophilia A in relation to previous treatment schedule of primary or secondary prophylaxis with start at different ages, comparing to subjects who received only on-demand therapy

Inclusion criteria

  • Severe hemophilia A (< 1% FVIII:C)

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