Drug Interaction Between Colchicine and Calcineurin Inhibitors in Renal Graft Recipients

Mise à jour : Il y a 4 ans
Référence : NCT01160276

Femme et Homme

  • | Pays :
  • France
  • | Organes :
  • -
  • | Spécialités :
  • -

Extrait

Ciclosporin inhibits P-glycoprotein should increase colchicine bioavailability whereas tacrolimus should not influence colchicine disposition. This is a prospective, controlled, open labeled study performed in renal graft recipients comparing colchicine single dose (1mg) pharmacokinetics in 14 patients treated with tacrolimus and 14 patients treated with cyclosporin.


Critère d'inclusion

  • Renal Replacement Therapies

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