Extrait

Background and study aims Current treatments for smokers do not typically address the behaviours and sensations associated with the act of smoking (e.g. handling a cigarette, inhaling, taste and feel of smoke on the throat). Electronic cigarettes (EC) are battery-operated devices that attempt to mimic the act of smoking and so provide these effects. EC can alleviate urges to smoke, but it is not known whether they are as effective at helping smokers who want to cut down on their smoking and quit as the existing stop-smoking medicines (e.g. nicotine replacement treatment (NRT)). The aim of this study is to compare the effectiveness of two different stop-smoking strategies: an electronic cigarette (EC) or a nicotine-replacement product (NRT). Who can participate? People at least 18 years old, who have failed to stop smoking with stop-smoking services and/or products in the past What does the study involve? Information is collected about participants’ smoking, mood and health, and the amount of carbon monoxide (CO) in their breath is measured (this shows how much smoke they inhale). Participants are then randomly allocated to use EC or NRT for at least 4 weeks. All participants are contacted by phone at weeks 1, 4 and 24 and asked questions about their mood, smoking and the use of their allocated product. Those who have reduced their smoking by 50% or more at weeks 4 and 24 are invited to the clinic for a CO reading and are given £10 towards the travel cost. What are the possible benefits and risks of participating? Participants receive either NRT or EC with behavioural support which they might find beneficial in helping them to quit or reduce their smoking. No risks are expected from using EC or NRT. Neither contain tobacco, and therefore do not deliver the many harmful substances found in normal cigarettes. As a result they pose no increased risk compared to normal cigarettes. The most common side effects that people report experiencing when using EC or NRT are mouth and throat irritation, nausea and sleep disturbance. The EC provided are not currently licensed as a medicine, but they are regulated as a consumer product. Where is the study run from? Queen Mary University of London (UK) When is the study starting and how long is it expected to run for? January 2017 to January 2018 Who is funding the study? Cancer Research UK Who is the main contact? Ms Marzena Orzol [email protected]

Critère d'inclusion

• SMOKING CESSATION

Liens

• isrctn