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A factorial randomised trial of blood pressure lowering with a fixed low-dose perindopril-indapamide combination and intensive glucose control with a modified-release gliclazide-based regimen for the ...

Update Il y a 4 ans
Reference: EUCTR2005-003281-41

A factorial randomised trial of blood pressure lowering with a fixed low-dose perindopril-indapamide combination and intensive glucose control with a modified-release gliclazide-based regimen for the prevention of vascular disease among high risk individuals with type 2 diabetes

Woman and Man

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Extract

To determine the effects of a fixed low-dose perindopril-indapamide combination (2mg/0.625mg) vs placebo and a modified-release gliclazide (30-120mg)-based intensive glucose lowering regimen vs standard guidelines-based therapy on major macrovascular and microvascular complications among individuals with type 2 diabetes over a scheduled mean treatment period of 4.5 years.

Inclusion criteria

  • type II diabetes mellitus

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