Phase: withdrawn
Peter Collins, MD, FRCP Update Il y a 5 ans

Hypnotherapy in Patients With Chest Pain & Unobstructed Coronaries This study will investigate whether clinical hypnotherapy can effectively treat chest pain symptoms, improve emotional wellbeing and quality of life in postmenopausal women with chest pain and coronary arteries without any narrowings. The diagnosis of chest pain with 'normal' coronary arteries is found in 25% of patients undergoing investigation of chest pain using coronary angiography (when dye is injected into the coronary arteries whilst xray pictures are taken), and the majority of these patients are postmenopausal women. Often there is no obvious physical cause. Despite symptoms being treated using conventional drugs, and life expectancy is not affected, many patients continue to suffer from debilitating chest pain symptoms, frequently resulting in visits to hospital, increased psychological illness and poor quality of life. The investigators are interested in finding ways of improving not only chest pain symptoms but also psychological wellbeing and quality of life in these patients. Previous studies of ours have found improvement in these patients after taking part in a support group, and using a relaxation technique called Autogenic training. Recently the investigators conducted a pilot study which showed a favourable effect of hypnotherapy on physical ability, well-being and quality of life. The investigators would now like to extend this study, performing a larger randomised, controlled trial. The investigators hypothesise that hypnotherapy will beneficially affect symptoms and quality of life in patients with cardiac Syndrome X.

  • Country None
  • organs None
  • Specialty None
Closed trial
Marguerite M Engler, Ph.D Update Il y a 5 ans

Study of the Effects of Blackcurrant Extract and Omega-3 Fats on the Health of the Heart and Blood Vessels Background: - Heart disease is the leading cause of death in the United States. Eating fruits and vegetables with chemicals called flavonoids may protect against heart disease and improve blood flow to the heart. They are found in blackcurrant berries. Oils found in fish and mussels called omega-3 fats have also been shown to protect the heart. Researchers want to know if blackcurrant extract and omega-3 fats can improve blood flow, which may increase blood to the heart. They also want to learn about the health of blood vessels and how the heart works. Objective: - To learn if blackcurrant extract and omega-3 fats will improve blood flow and make the heart beat stronger. Eligibility: - Healthy adults 55 to 75 years old. Design: - Participants will be screened with medical history, physical exam, and blood tests. - Visit 1 will take 6 7 hours. - Participants will have physical exam and blood and urine tests. - A small device like a microphone will be placed on their arm to take pictures of blood vessels. A blood pressure cuff will be tightened on their arm and more pictures will be taken. - Blood pressure cuffs will be placed on their arms and legs. They will be tightened at the same time and blood pressure will be measured. - Participants will answer questions about their eating and exercise. - Every 8 weeks, participants switch from taking blackcurrant and/or omega-3 tablets to a placebo to no tablets. <TAB> - Every 8 weeks, they will have another shorter clinic visit that will repeat most of visit 1.

  • Country None
  • organs None
  • Specialty None
Closed trial