Comparison of increasing doses of tapentadol vs a combination of tapentadol and pregabalin The primary objective is to evaluate the effectiveness, safety, and tolerability of increasing doses of tapentadol PR (300 mg per day after run-in, up-titration to 500 mg per day) versus a combination...

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An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with severe chronic pain due to osteoarthritis of the knee taking WHO Step III analgesics but showing a lack of tolerability Primary objective is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride PR in subjects with chronic pain due to osteoarthritis of the knee pretreated with WHO Step III...

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An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with uncontrolled severe chronic nociceptive, mixed or neuropathic low back pain taking either WHO Step I or Step II analgesics or no regular analgesics To evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride PR in subjects with severe chronic nociceptive, mixed or neuropathic low back pain showing lack of efficacy under pr...

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Comparison of tapentadol PR and oxycodone/naloxone PR Tapentadol LP en comparación con oxicodona/naloxona LP The primary objective is to evaluate the effectiveness, safety, and tolerability of tapentadol PR versus oxycodone/naloxone PR in non-opioid pre-treated subjects with uncontrolled severe chronic low b...

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Safety and efficacy of lidocaine 5% medicated plaster in comparison with pregabalin in postherpetic neuralgia and diabetic polyneuropathic pain The primary objective of this trial is to evaluate the safety and efficacy of lidocaine 5% medicated plaster versus pregabalin after 4 weeks of treatment in subjects with postherpetic neuralgia and di...

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A 4-week trial evaluating the efficacy, safety, and tolerability of GRT6005, a new centrally acting analgesic, in subjects with moderate to severe pain due to osteoarthritis of the knee To explore the analgesic efficacy of fixed doses of 75 µg, 200 µg, and 400 µg GRT6005 once daily compared to placebo in subjects with moderate to severe pain due to OA of the knee.

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Grunenthal 672519 : Essai de phase 3 randomisé, en double aveugle comparant l’efficacité et la tolérance d’un traitement antidouleur, à la morphine, par CG5503, chez des patients ayant une tumeur maligne. [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions] A randomized withdrawal, active- and placebo-controlled, double-blind, multi-center phase III trial assessing safety and efficacy of oral CG5503 PR in subjects with moderate to severe chronic malignan...

• Pays France
• Organes Tout Cancer
• Spécialités Autres (cryothérapie, radiofréquence, homéopathie,...)

An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with uncontrolled severe chronic pain due to osteoarthritis of the knee taking either WHO Step I or Step II analgesics or no regular analgesics To evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride PR in subjects with chronic pain due to OA of the knee taking either WHO Step I or Step II analgesics or no regular ...

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A four-week trial evaluating the efficacy, safety and tolerance of GRT6005, a new centrally acting analgesic, in patients with pain due to diabetic nerve damages To evaluate the analgesic efficacy of fixed doses of 25 µg, 75 µg, and 200 µg GRT6005 once daily compared to placebo in subjects with moderate to severe pain due to diabetic polyneuropathy.

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not applicable The primary objective of this trial is to describe the safety and tolerability of prolonged exposure to cebranopadol in subjects suffering from cancer related pain

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