Risk adapted treatment of Acute Myelocytic Leukaemia (AML) Not provided at time of registration

• Pays Netherlands
• Organes Aucun
• Spécialités Aucune

A Randomized Controlled Study of Docetaxel Monotherapy or Docetaxel and DOXIL for the Treatment of Advanced Breast Cancer The primary objective of this study is to evaluate whether the overall survival for the DOXIL/CAELYX and docetaxel treatment group is superior to that of the group treated with docetaxel monotherapy

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

A comparison of the effectiveness and safety of topiramate and phenytoin in patients with new onset epilepsy requiring rapid initiation of antiepileptic drug treatment The purpose of this study is to compare the effectiveness and safety of two treatment regimens, topiramate as compared to phenytoin, in preventing seizures in patients with new-onset epilepsy who requ...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

A Safety Study of Mebendazole in Children 2 to 10 Years of Age The primary objective of this study was to assess the safety and tolerability of a mebendazole 500-mg chewable tablet formulation in a pediatric population (children 2 to 10 years of age, inclusive).

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

A One-Year, Randomized, Open-Label, Parallel-Arm, Phase III Long-Term Safety Trial, with Controlled Adjustment of Dose, of Multiple Doses of CG5503 PR* and Oxycodone CR in Subjects with Chronic Pain The primary objective of the trial is the evaluation of the safety profile of CG5503 PR base at doses ranging between 100 mg and 250 mg BID over long term exposure of up to one year.

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

A DOUBLE BLIND, PLACEBO CONTROLLED, RANDOMIZED, SEQUENTIAL GROUP, MULTIPLE DOSE STUDY OF THE EFFICACY OF THE CRF1-RECEPTOR ANTAGONIST R317573 ON CCK-4 INDUCED ANXIETY IN HEALTHY MALE SUBJECTS To determine whether R317573, after multiple dosing over one week, reduces the intensity of an anxiogenic reaction induced by the intravenous (i.v.) administration of cholecystokinin-tetrapeptide (CCK...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

PROtease modulating dressings in the treatment of chronic wounds: finding bioMARKers to predict healing response Not provided at time of registration

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

J&J CR015769 : Essai de phase 3 randomisé comparant l'efficacité de la trabectedin à une chimiothérapie à base de doxorubicine, en traitement de 1ère ligne, chez des patients ayant un sarcome des tissus mous avec translocation chromosomique, [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions] A randomized, multicenter, phase III trial of trabectedin (Yondelis) versus doxorubicin-based chemotherapy as first-line therapy in patients with translocation-related sarcomas (TRS)

• Pays France
• Organes Sarcomes
• Spécialités Chimiothérapie

Comparison of two different surgical approaches to decompress lumbar spinal nerves in patients with narrow lumbar spinal canal and instability Background and study aims Spinal fusion surgery (spondylodesis) is a type of surgical procedure which joins two or more vertebrae (small bones that make up the spine) together. It is more often used t...

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

JOHNSON&JOHNSON CR016057 : Essai de phase 2 randomisé, en double aveugle, comparant l'efficacité et la tolérance du JNJ-42160443 à un placebo dans le traitement de la douleur, chez des patients ayant un cancer. [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions] A randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy, safety, and tolerability of JNJ-42160443 as adjunctive therapy in subjects with cancer-related pain, followe...

• Pays France
• Organes Tout Cancer
• Spécialités Autres (cryothérapie, radiofréquence, homéopathie,...)